EFFECTS OF RICIN TOXIN FROM CASTOR OIL SEED EXPOSURE ON THE LIVER OF ADULT WISTAR RATS

Abstract

This study was designed to evaluate the effects of ricin toxin from castor oil seeds on Histology of experimental rats liver (Albino) for the benefits of reducing rodents pest population. The results shows a significant (p<0.05) highest liver weight in rats fed with control feed (8.83a) when compared with rat fed with ricin toxin from castor oil seed (6.50b), (5.25 c), (4.58c), (4.50c) and is clearly seen that increase in the dose and the function of a ricin toxin from castor oil seed affected the liver weight of tested rats.The result of all test liver showed histological features of lethal tissue damage in all the rat treated with ricin toxin examined. The control group showed normal tissue. The present findings clearly demonstrate that extract from castor oil seed is capable of inducing histopathological changes in the liver of the exposed rats. According to these results, it is suggested that plant with toxins like ricin exposure might cause hazardous effects, especially to living organisms.